TRANSIL Brain Absorption: An in vitro model for predicting CNS penetration. Presentation at the 15th annual SBS meeting held in Lille.
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Presentation of applications for Sovicells in vitro assay for CNS absorption at the SMI conference on "High Throughput Screening for Biological Systems" in London.
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Presentation of validation data for the TRANSIL Brain Absorption kit for predicting the brain free fraction and the brain-to-plasma distribution at the LogP2009 meeting in Zürich.
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Presentation of pre-clinical applications of the TRANSIL High Protein Binding Assay for plasma protein binding of small molecules and peptides at the predictive human toxicity/ADME-Tox meeting in Brussels.
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Congratulations to the winner of the iPod raffle held at the ADME-Tox Europe meeting in Stockholm! His name is Dr. Markus Probst.
The TRANSIL blood-to-brain absorption kit can be used both to assess the ability of compounds to permeate the blood brain barrier and to predict the equilibrium distribution of compounds between blood and brain. Using a structurally rather diverse test set of drugs it is shown that the test kit’s predictions correlate strongly with in vivo data.
Nimbus Biotechnology brings the first ready-to-use assay kit for analyzing drug candidates ability to cross the blood brain barrier to the market.