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2/28/2008Nimbus changes name to Sovicell and launches new website2/20/2008Sovicell announces winner of the iPod raffle1/25/2008Presentation of first validation data for the TRANSIL blood-to-brain absorption kit at the predictive human toxicity/ADME-Tox meeting in Brussels9/1/2007Release of TRANSIL Blood-to-Brain absorption kit

Products

Membrane Permeability

  • TRANSIL Intestinal Absorption kit
  • TRANSIL Blood-to-Brain Absorption kit

TRANSIL Intestinal Absorption kit

Our TRANSIL Intestinal Absorption kit evaluates the membrane affinity of a drug candidate, which is directly related to permeation, and thereby assesses its ability to cross the intestinal epithelium. This is possible as the membranes in our TRANSIL Intestinal Absorption kit closely mimic the natural composition and physiological behaviour of the intestinal epithelium.

TRANSIL Blood-to-Brain Absorption kit

Development of CNS drugs requires knowledge of a lead compound’s ability to cross the blood-brain barrier and, more frequently, this knowledge is also becoming essential in other therapeutic areas to prevent side effects. The TRANSIL Brain Absorption kit assesses a drug candidate’s ability to cross the blood brain barrier by directly measuring its affinity for the brain’s membrane. Membrane affinity is directly related to permeation and blood-to-brain absorption of a drug.

Advantages of TRANSIL:

  • Rapid - 2 min incubation
  • Ready to use format
  • Easy to use
  • Highly reproducible
  • Accurately mimics in vivo physiology
  • Suitable for high throughput

To order your membrane permeability kits contact orders@sovicell.com.

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