Our TRANSIL Intestinal Absorption kit evaluates the membrane affinity of a drug candidate, which is directly related to permeation, and thereby assesses its ability to cross the intestinal epithelium. This is possible as the membranes in our TRANSIL Intestinal Absorption kit closely mimic the natural composition and physiological behaviour of the intestinal epithelium.
Development of CNS drugs requires knowledge of a lead compound’s ability to cross the blood-brain barrier and, more frequently, this knowledge is also becoming essential in other therapeutic areas to prevent side effects. The TRANSIL Brain Absorption kit assesses a drug candidate’s availability in brain by measuring the brain free fraction and the brain-to-plasma distribution coefficient. The estimated availability is proportional to the free concentration in brain.
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Advantages of TRANSIL:
To order your membrane permeability kits contact orders@sovicell.com.
