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Membrane Permeability
Protein Binding
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Trusted ADMET
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News

2/28/2008Nimbus changes name to Sovicell and launches new website2/20/2008Sovicell announces winner of the iPod raffle1/25/2008Presentation of first validation data for the TRANSIL blood-to-brain absorption kit at the predictive human toxicity/ADME-Tox meeting in Brussels9/1/2007Release of TRANSIL Blood-to-Brain absorption kit

Products

ADMET products for detailed pharmocokinetic profiling.

Our state-of-the-art products for drug discovery and development include a range of in vitro TRANSIL assay kits for membrane permeability and protein binding studies and SOVICYTE cell lines for drug metabolism and cytotoxicity studies, enabling early and accurate prediction of the efficacy and safety of drug candidates.

product overview

The numerous membrane permeability and protein binding assays that we offer are underpinned by our TRANSIL technology platform. This comprises a bead based system that mimics certain physiological conditions of the human body allowing Absorption (membrane permeability) and Distribution (protein binding) of drug candidates to be easily and reproducibly assessed.

Major pharmaceutical companies have adopted our TRANSIL technology and we are continually developing further products in collaboration with our customers to meet their needs.

The latest addition to our TRANSIL product line is our blood-to-brain absorption kit which is based on natural brain biological membranes, and is the only product of its kind that is currently available on the market.

SOVICYTE Human Cryopreserved Hepatocytes are the first product in our recently launched SOVICYTE product range which covers the different aspects of metabolic transformation, allowing detailed metabolism studies of drug candidates and other test substances as well as cytotoxicity studies.

Our high quality hepatocytes yield reliable results on metabolic parameters and hepatotoxicity.

Please contact us if you require more information about our products and reagents or customized kits.

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